By Kenneth S. Korach
ISBN-10: 0824798570
ISBN-13: 9780824798574
This well timed source deals large discussions at the pharmacological, environmental,endocrinological, and common components that modify reproductive or developmental processes-elucidating the consequences of toxicants on mechanisms of copy. Describing organic activities universal to either genders in addition to gender-specific strategies, Reproductive and Developmental Toxicology ·provides an summary of the elemental biology and body structure of organ structures tormented by toxicants ·furnishes special examples of developmental toxicology ·analyzes germ mobile toxicity and infertility ·covers the developmental results of neurotoxicity ·considers classes of publicity and long term toxicological results ·explains how gonadal strategies could be liable to toxicants in different reproductive organ platforms ·and extra! With over 3700 bibliographic citations and greater than a hundred images, drawings, and tables, Reproductive and Developmental Toxicology is an invaluable reference for toxicologists; reproductive, developmental, phone, and molecular biologists; endocrinologists; biochemists; obstetricians/gynecologists; pediatricians; pharmacists and pharmacologists; physiologists; geneticists; poison regulate experts; and upper-level undergraduate, graduate, and clinical institution scholars in those disciplines.
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Goldman, and Lee Tyrey 195 Page viii 10. Developmental Neurotoxicology Gaylia Jean Harry 211 11. Lead Neuroendocrine Toxicology Rebecca Z. Sokol 249 Part II. Female Reproduction 12. Female Reproduction and Toxicology of Estrogen James H. Clark 259 13. Phytoestrogens and Reproductive Medicine Claude L. , and Ginger Tansey 277 14. Human Health and Phytoestrogens Herman Adlercreutz 299 15. Ovarian Toxicants: Multiple Mechanisms of Action Barbara J. Davis and Jerrold J. Heindel 373 16. Toxicology of Early Pregnancy, Implantation, and Uterine Function Audrey M.
A) Rat oviduct immediately postovulation. The ovum (o) is surrounded by follicular cells (fc), which have aided in egg obtainment by the oviduct (Fallopian tube, ft) through interactions with the epithelial lining. The ovum (o) is about 100 mm in diameter. H+E stained fixed tissue section. (B) The mouse one-cell stage about 14 h after fertilization. The arrow indicates one of the polar bodies, which is in the perivitelline space defined by the zona pellucida (zp). A pronucleus is apparent in the center of the fertilized egg which is about 100 mm in diameter.
W. (1994). Nature, 369: 455. Lee, ML, Donahoe, P. , Crist, G. , Noto, R. , MacLaughlin, D. T. (1996). J. Clin. Endocrinol. Metab. 81: in press. Leibowitz, M. , and Wickner, R. B. (1976). Proc. Natl. Acad. Sci. USA, 89: 73. Liu B, Goltzman D, Rabbani SA. (1995). Am. J. Physiol. 268: E832. MacLaughlin, D. , Hudson, P. , Graciano, A. , Kenneally, M. , Ragin, R. , Manganaro, T. , and Donahoe, P. K. (1992a). Endocrinology, 131: 291. MacLaughlin, D. , Levin, R. , Catlin, E. , Taylor, L. , Preffer, F.
Reproductive and developmental toxicology by Kenneth S. Korach
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