Download e-book for kindle: Chemical Warfare Agents: Toxicology and Treatment by Timothy T. Marrs, Robert L. Maynard, Frederick R. Sidell

By Timothy T. Marrs, Robert L. Maynard, Frederick R. Sidell

ISBN-10: 0470013591

ISBN-13: 9780470013595

ISBN-10: 0470060026

ISBN-13: 9780470060025

Chemical battle brokers, moment variation has been absolutely revised because the profitable first version and extended to approximately 3 times the size, with many new chapters and masses extra in-depth attention of the entire subject matters. The chapters were written through exceptional overseas specialists in a number of facets of chemical war brokers and edited by means of an skilled group to supply a transparent assessment of the field.The publication now incorporates a wealth of fabric at the mechanisms of motion of the most important chemical conflict brokers, together with the nerve agent cyclosarin, officially thought of to be of secondary significance, in addition to ricin and abrin. Chemical struggle brokers, moment variation discusses the physico-chemical homes of chemical conflict brokers, their dispersion and destiny within the setting, their toxicology and administration in their results on people, decontamination and protecting apparatus. New chapters hide the adventure received after using sarin to assault guests at the Tokyo subway and the way to house the result of the deployment of insurrection keep an eye on brokers reminiscent of CS gas.This booklet offers a finished evaluate of chemical struggle brokers, assessing all on hand proof in regards to the clinical, technical and criminal points in their use. it really is a useful reference paintings for physicians, public healthiness planners, regulators and the other pros inquisitive about this field.Review of the 1st Edition:"What extra applicable time for a identify of this scope than within the submit 11th of September period? ...a well timed, scholarly, and well-written quantity which deals a lot info of huge present and…future benefit."—VETERINARY AND HUMAN TOXICOLOGY

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Read e-book online Loomis's Essentials of Toxicology PDF

By Ted A. Loomis

ISBN-10: 0080535631

ISBN-13: 9780080535630

ISBN-10: 0124556256

ISBN-13: 9780124556256

Loomis's necessities of Toxicology is an introductory textual content at the technological know-how of damaging biologic results linked to exposures to chemical compounds of every kind. The scope of this publication incorporates a dialogue of the foremost kinds of chemical compounds concerned; the final homes of chemical substances and biologic platforms as they impact the incidence of damaging biologic results; the tools used to illustrate those results; and the root for medical analysis and treatment of damaging results of chemical compounds on people. person examples are used to illustrate all the ideas below dialogue. this article is a useful source for toxicologists in addition to a accomplished advent to the subject for graduate and complex undergraduate scholars in toxicology and public future health. Key gains * The ''classic textbook'' in toxicology * thoroughly revised and up to date * comprises either ideas and strategies * calls for minimum history in chemistry and biology

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Download e-book for kindle: Endocrine disruptors : effects on male and female by Rajesh K. Naz

By Rajesh K. Naz

ISBN-10: 0849322812

ISBN-13: 9780849322815

"Endocrine Disruptors: results on female and male Reproductive structures, moment version examines the reproductive and future health risks of endocrine-disrupting environmental chemical compounds from epidemiology to etiology, concluding with destiny instructions. prime experts give a contribution specialist analyses and up to date info on an issue that has turn into an incredible problem one of the medical neighborhood and the final public." Read more...

content material: part I impression at the woman Reproductive process --
Disruption of Nongenomic Steroid activities on Gametes and Serotonergic Pathways Controlling Reproductive Neuroendocrine functionality by way of Environmental chemical substances --
Developmental and Reproductive Abnormalities linked to Environmental Estrogens: Diethylstilbestrol (DES) for example Ovotoxic Environmental chemical compounds: oblique Endocrine Disruptors --
p,p'-DDE and HCB: Mechanisms of Toxicity to Fetal and Embryonic Mammalian Cells --
nutritional Phytoestrogens --
Estrogens, Xenoestrogens and the improvement of Neoplasms --
Molecular Mechanisms of Endocrine Disruption in Estrogen established methods --
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and comparable Environmental Antiestrogens: Characterization and Mechanism of motion --
part II impact at the Male Reproductive procedure --
Endocrine Disruptors and Male Infertility --
Environmental Androgens and Antiandrogens: An increasing Chemical Universe --
Endocrine Disruptors and Male Sexual disorder --
Prostate improvement: Mechanisms for contrary results of high and low Doses of Estrogenic chemical substances --
steel Ions as Endocrine Disruptors: Implications for Prostate Cancer.
summary: "Endocrine Disruptors: results on female and male Reproductive platforms, moment version examines the reproductive and healthiness risks of endocrine-disrupting environmental chemical substances from epidemiology to etiology, concluding with destiny instructions. top professionals give a contribution specialist analyses and up to date info on a subject that has turn into an immense main issue one of the medical neighborhood and the final public." "Divided into sections, the 1st a part of the booklet describes the results of environmental toxicants at the lady reproductive process, with an emphasis at the results and mechanisms in their motion on intercourse differentiation in the course of improvement, fertility, and breast melanoma. the second one half addresses the results of endocrine disruption at the male reproductive process, concentrating on male fertility and the advance of benign prostate hyperplasia (BPH) and prostate cancer."--BOOK JACKET

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Get Medical Primatology: History, Biological Foundations and PDF

By Eman P Fridman, Ronald D. Nadler

ISBN-10: 0203218698

ISBN-13: 9780203218693

ISBN-10: 0203274091

ISBN-13: 9780203274095

ISBN-10: 0415275830

ISBN-13: 9780415275835

As a result excessive measure of organic similarity among primates and people, monkeys and apes were used effectively in scientific study for plenty of many years. clinical Primatology: heritage, organic Foundations and purposes presents a complete precis linking using monkeys and apes in biomedical learn to their kinship with people. The booklet starts via discussing the heritage of this learn, after which specializes in the organic foundations upon which scientific primatology has been outfitted. Primate taxonomy and evolution are reviewed, utilizing not just conventional resources of knowledge, but additionally contemporary experimental proof from molecular biology, genetics, and biomedicine that shows the necessity to position larger simians within the relatives of guy. Condensing a vast diversity of clinical literature into one quantity, this can be an invaluable reference for experts within the organic sciences and drugs, in addition to researchers excited about organic, anthropological, biomedical, scientific, and pharmacological examine on primates.

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W. Norman Aldridge's Mechanisms and Concepts in Toxicology PDF

By W. Norman Aldridge

ISBN-10: 0748404139

ISBN-13: 9780748404131

Specializes in study strategies in toxicology, aiming to demonstrate strategies and kinds of toxicity from a mechanistic standpoint. Examples of chemical intoxicants are used to demonstrate mechanisms in each one level of toxicity.

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Download e-book for iPad: Poisoning and Drug Overdose by Kent Olson

By Kent Olson

ISBN-10: 0838581722

ISBN-13: 9780838581728

The simplest guide at the analysis and therapy of poisoning and drug overdose. completely up to date, this reference gains wide tables summarizing toxicity and office publicity directions for over 500 commercial chemical substances, an index containing the components of over a hundred and fifty universal advertisement items, and tabs for fast reference.

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Ludwig A. Hothorn's Statistics in Toxicology Using R PDF

By Ludwig A. Hothorn

ISBN-10: 1498701280

ISBN-13: 9781498701280

The obvious contradiction among statistical importance and organic relevance has reduced the worth of statistical tools as an entire in toxicology. furthermore, suggestions for statistical research are vague in such a lot toxicological instructions. Addressing those dilemmas, Statistics in Toxicology utilizing R explains the statistical research of chosen experimental info in toxicology and provides assay-specific feedback, akin to for the in vitro micronucleus assay.

Mostly concentrating on speculation checking out, the booklet covers standardized bioassays for chemical compounds, medicinal drugs, and environmental toxins. it really is geared up in response to chosen toxicological assays, together with:

  • Short-term repeated toxicity studies
  • Long-term carcinogenicity assays
  • Studies on reproductive toxicity
  • Mutagenicity assays
  • Toxicokinetic reports

The booklet additionally discusses facts of security (particularly in ecotoxicological assays), toxicogenomics, the research of interlaboratory reviews and the modeling of dose-response relationships for possibility review. for every toxicological challenge, the writer describes the information concerned, matching facts instance, R code, and results and their interpretation. This technique lets you choose a undeniable bioassay, determine the explicit facts constitution, run the R code with the information instance, comprehend the try out consequence and interpretation, and exchange the knowledge set along with your personal info and run again. 

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Download e-book for iPad: Human Developmental Toxicants: Aspects of Toxicology and by James L. Schardein (Author), Orest T. Macina (Author)

By James L. Schardein (Author), Orest T. Macina (Author)

ISBN-10: 0849372291

ISBN-13: 9780849372292

ISBN-10: 1420006754

ISBN-13: 9781420006759

Offering the 1st database of its type, this specific reference illustrates the relationships among the chemistry and developmental toxicity of a few vital prescribed drugs and commercial toxicants. Human Developmental Toxicants comprises up to date and concise details at the chemical buildings, houses, and organic actions for fifty recognized brokers that adversely impact prenatal and postnatal human improvement when it comes to development, viability, constitution, and serve as. This e-book offers info linking chemical and structural homes of particular toxicants as they relate to poisonous results, dosage, timing, and direction of publicity. concentrating on one compound in line with bankruptcy, the e-book additionally contains linked organic info from animals for every agent coated. An accompanying CD summarizes all the facts mentioned within the textual content inside an digital database. additionally, the CD comprises 3-dimensional constitution representations and forty nine calculated physicochemical and topological parameters of the chosen molecules. this knowledge comes in handy for development constitution job courting (SAR) versions linking the chemical homes with saw human developmental toxicity. As scientists proceed to discover how chemical compounds adjust human improvement, Human Developmental Toxicants includes the mandatory info to extra determine which chemical houses are accountable for opposed results. This reference offers toxicologists, teratologists, chemists and different scientists with the newest info and data had to practice probability checks, are expecting chemical substances which can produce developmental toxicity, and control damaging publicity.

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