By Michael Aschner, Lucio G. Costa
ISBN-10: 0849317940
ISBN-13: 9780849317941
Providing the most recent examine in glial mobile functionality gleaned from new strategies in imaging and molecular biology, The function of Glia in Neurotoxicity, moment version covers a number of features of glial cells, together with morphology, body structure, pharmacology, biochemistry, pathology, and their involvement within the pathophysiology of neurological ailments. The publication is established to check the interactions among glial cells and neurons in the course of improvement, maturity, and senescence, by way of particular examples of without delay mediated glial neurotoxicity. The ebook additionally covers miscellaneous themes in glial physiology/biochemistry resembling signaling and edema. The publication contains insurance of advances in our wisdom and knowing of glial body structure and biochemistry. realize what is new within the moment Edition:Neuronal-glia metabolic interactionsNeuronal-glia interactions (glutamate homeostasis)Zinc transporters in gliaEnergy deprivation/mitochondrial disorder - precise astrocyte susceptibilitiesAstrocytes and MPTP neurotoxicityAstroglia and foodstuff toxinsCurrent knowing of the significance of glia has brought on a increase in released info. but whereas a few of the released textbooks are multifaceted and multidisciplinary, none contains the position of glia in neurotoxicity. Written by way of leaders within the box of glial examine, this article fills this lacking hole within the literature. Broader in scope than the 1st version, together with contributions from the world over recognized researchers, this is often nonetheless the single publication devoted to exploring the position of glial cells in mediating neurotoxicology.FeaturesSummarizes the most recent study in glial mobilephone functionality gleaned from new strategies in imaging and molecular biologyContains tables and figures that offer you quickly and simple entry to specific dataIncludes a modern precis of literature that places info invaluable for furnish submissions at your fingertipsFeatures new chapters protecting metabolic interactions, glutamate homeostasis, transporters, power deprivation/mitochondrial disorder, astrocytes, and nutrients pollutants Explores the function of glial cells in mediating neurotoxicity and accommodates details on particular results of many compounds
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Read e-book online The Role of Glia in Neurotoxicity, Second Edition PDF
Offering the newest study in glial phone functionality gleaned from new ideas in imaging and molecular biology, The function of Glia in Neurotoxicity, moment version covers a number of elements of glial cells, together with morphology, body structure, pharmacology, biochemistry, pathology, and their involvement within the pathophysiology of neurological illnesses.
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Extra resources for The Role of Glia in Neurotoxicity, Second Edition
Example text
155, 337, 1993. 15. , Gestational exposure to methylmercury alters the developmental pattern of trk-like immunoreactivity in the rat brain and results in cortical dysmorphology, Brain Res. Dev. , 109, 13–31, 1998. 16. , Gestational exposure to methylmercury alters the developmental pattern of trk-like immunoreactivity in the rat brain and results in cortical dysmorphology, Brain Res. Dev. , 109, 13–31, 1998. 17. , Ciliary neurotrophic factor enhances the rate of oligodendrocyte generation, Mol.
J. , 330, 613– 622, 1994. 110. , Oligodendrocyte and astrocyte development in rodents: an in situ and immunohistological analysis during embryonic development, Glia, 40, 25, 2002. 111. , Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection, Cell, 109, 75, 2002. 112. , Ethanol blocks both basic fibroblast growth factor- and carbachol-mediated neuroepithelial cell expansion with differential effects on carbachol-activated signaling pathways, Neuroscience, 118, 37, 2002.
8, S175, 2003. 43. , 56, 2405, 1996. 44. , Aberrant CpG-island methylation has non-random and tumour-typespecific patterns, Nat. , 132, 2000. 45. , 17, 49, 2000. 46. , 18, 701, 1998. 47. , Benchmark concentrations for methylmercury obtained from the Seychelles Island Development Study, Environ. , 108, 257, 2000. 48. , The antioxidants J811 and 17 estradiol protect cerebellar granule cells from methylmercury induced apoptotic cell death, J. Neurosci. , 62, 557–565, 2000. 49. , Astrocytes as mediators of methylmercury neurotoxicity: effects on D-aspartate and serotonin uptake, Dev.
The Role of Glia in Neurotoxicity, Second Edition by Michael Aschner, Lucio G. Costa
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