By Costas Ioannides
ISBN-10: 0471894664
ISBN-13: 9780471894667
This definitive reference paintings describes intimately the enzyme platforms that perform the metabolism of xenobiotics, relatively medicines. every one bankruptcy makes a speciality of a particular enzyme method, emphasising its function within the activation and detoxication of chemical substances. facets mentioned seriously comprise: enzyme functionality within the metabolism and bioactivation of xenobiotics substrate specificity tissue distribution species distribution (to contain laboratory animals and people) hormonal rules intercourse ameliorations modulation via earlier publicity to different chemical substances age-dependent expression pharmacogenetics and modulation through disorder. Enzyme structures that Metabolise medicines and different Xenobiotics might be crucial analyzing for commercial examine scientists operating within the effective chemical substances and pharmaceutical industries, specifically these interested in the protection assessment of chemical substances, and investigating their metabolism, pharmacokinetic features and toxicological homes. the character and scope of the e-book also will make it appealing to the examine toxicologist and to postgraduate scholars learning toxicology, in addition to to clinicians and pharmacists.
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Enzyme Systems that Metabolise Drugs and Other Xenobiotics by Costas Ioannides
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