By J. J. Emeis, E. Wisse (auth.), Nicholas R. Di Luzio, Kurt B. P. Flemming (eds.)
This quantity represents a part of the court cases of the 6th overseas assembly of the Reticuloendothelial Society. there's no doubt that the college of Freiburg was once a perfect selection because the website of the assembly when you consider that, in essence, the Society was once based right here whilst Aschoff undertook his classical stories at the macrophage and came upon what may perhaps were the final ultimate organic process. within the approximate fifty years that have elapsed considering that Aschoff brought the descriptive time period Reticuloendothelial process to unify these cells with the typical estate of phagocytosis, one reveals investigative task on the optimum point in all components of reticuloendothelial involvement. certainly, the subjects coated within the current quantity might of necessity require that the typical estate of phagocytosis which resulted in the formula of the reticuloendothelial method be changed. the typical foundation at this time is obviously not phagocytic expression, however the unifying foundation of host safety. The totality of reticuloendothelial involvement in host-defense is obviously mirrored by way of the various clinical backgrounds and examine pursuits of the members of the assembly. awesome advances in appreciating the involvement of the RES in keeping the health of the host opposed to quite a few endogenous and exogenous elements were made considering that quantity I of the Advances in Experimental Biology and drugs at the reticulo endothelial process was once published.
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Additional info for The Reticuloendothelial System and Immune Phenomena: Proceedings of the Ludwig Aschoff Memorial Meeting of the Reticuloendothelial Society, Freiburg, Germany, August 1970
Cytochemistry (Figs. 1 and 2). After incubation for the demonstration of peroxidase activity, electrondense reaction product was found in about 90 %of the resident macrophages. It was characteristically present in the cisternae of the rough endoplasmic reticulum, in the nuclear envelope, and in some cisternae of the Golgi apparatus as well as in vesicles present in the Golgi area. 3 ~ containing reaction product was found. 01 M potassium cyanide showed no reaction product at all. The addition of amino-triazole also resulted in no staining of resident peritoneal macrophages.
I Fig. 4. Exudate peritoneal macrophage incubated in a complete medium for the demonstration of peroxidase activity, plus amino-triazole. In the Golgi area granules containing the reaction product (arrows) are present. The cell surface shows few of the slender projections so characteristic of the resident peritoneal macrophages (compare with Figs. 1 and 2). 000 28 STRUCTURE AND ORIGIN OF MACROPHAGES activity is also located in the endoplasmic reticulum and the nuclear envelope, and can similarly be prevented by adding amino-triazole to the incubation medium (11).
6 c 4 "g 0 :E ........ • 10 • 2 /4/. 0::: t~ 0 2 3 4 5 6 7 8 MONOCYTES _10-3 per ~l BLOOD Fig. - Monocyte turnover rate I plotted as a function of the monocyte count in the blood. more basophilic than in the first group of monocytes. 3) Monocytes with oval or round nucleus with a dense chromatin structure often containing nucleoli. The cytoplasma showed a marked basophilia and in some of the cells it contained promyelocyte like coarse granules. 1 %. 3 %. 6 % (Table 1). The number of the 3 monocyte forms increased-approximately in proportion to the monocyte count in the blood (Fig.
The Reticuloendothelial System and Immune Phenomena: Proceedings of the Ludwig Aschoff Memorial Meeting of the Reticuloendothelial Society, Freiburg, Germany, August 1970 by J. J. Emeis, E. Wisse (auth.), Nicholas R. Di Luzio, Kurt B. P. Flemming (eds.)