By Patricia Frank
ISBN-10: 0470381124
ISBN-13: 9780470381120
This re-creation of a widely-read and highly-acclaimed publication broadens the scope of its predecessors from a heavy concentrate on business chemical substances as toxicants to incorporate medicines, foodstuff ingredients, cosmetics and different sorts of compounds that folks are uncovered to day-by-day. additionally new to the 3rd version are more recent issues-of-the-day reminiscent of nanoparticulate toxicants, moment hand smoke, foodstuff illness, lead in toys, and others. As such, the e-book presents the fundamentals of toxicology in easy-to-understand language in addition to a fuller realizing of the day-by-day insults to which bodies are subjected.
Read or Download The Dose Makes the Poison: A Plain-Language Guide to Toxicology, 3rd Edition PDF
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Extra resources for The Dose Makes the Poison: A Plain-Language Guide to Toxicology, 3rd Edition
Sample text
Indd 28 12/16/2010 7:54:27 PM 29 DEFINITION OF HAZARD FIGURE 2-2 “Mr. Yuk” poison sign. Boric acid, which is a very effective roach killer, does not present a hazard when applied in powder form in spaces behind cabinets and under drawers where it is inaccessible. It can be very hazardous when combined with sugar and formed into tablets that are scattered around baseboards. A young child crawling around the kitchen floor can find and eat these tablets without being observed. Several hours later, when symptoms appear, the cause will not be known, and the urgency of getting medical attention will not be recognized.
WHY THE “GOOD-BAD” DICHOTOMY? What are the properties of synthetic chemicals that have fostered the dichotomy of man-made (bad) versus natural (good)? An exploration of this question is important to an understanding of the effects of chemicals on living organisms. The attributes of synthetic chemicals that set them apart from chemicals of natural origin were elegantly described years ago by the American biologist Barry Commoner: The clash between the economic success of synthetic petrochemicals and their increasing vulnerability to biological complaints is the inevitable result of the fact that they are synthetic-made by man, not nature.
EMPIRICAL TOXICOLOGY Empirical toxicology, as distinguished from the science of toxicology, predates recorded history. Prehistoric people knew which poisonous plants and animals to avoid from watching their fellow beings and by being educated by group elders. These experiences also told them which plant juices to use as toxins. The fact that certain substances could cause acute illness or death was known to even the earliest human populations because it was so obvious—the cause-effect relationship was so direct.
The Dose Makes the Poison: A Plain-Language Guide to Toxicology, 3rd Edition by Patricia Frank
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