By Harold I. Zeliger (Auth.)
ISBN-10: 0815515898
ISBN-13: 9780815515890
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"An easy-to-read booklet that are meant to be in any toxicologist's library. With a huge attempt of synthesis, the writer has handled a wide selection of topics within the rising box of chemical mixtures." -- Arturo Ortego, M.D., university of medication and overall healthiness Sciences, Rovira I Virgili collage, Reus, Spain
Content:
Preface
, Pages xxi-xxiii
1 - Introduction
, Pages 3-6
2 - healthiness results of Exposures to Chemical Mixtures
, Pages 7-15
3 - Absorption of Chemical Mixtures
, Pages 17-22
4 - Chemical Toxicology
, Pages 23-49
5 - Scope and resources of poisonous Exposures
, Pages 53-57
6 - In Utero Exposure
, Pages 59-62
7 - Air Pollution
, Pages 63-77
8 - Water Pollution
, Pages 79-119
9 - Soil Pollution
, Pages 121-127
10 - Food
, Pages 129-156
11 - chemical compounds in and round the Home
, Pages 157-174
12 - in poor health construction Syndrome
, Pages 175-195
13 - commercial Exposure
, Pages 197-211
14 - Pesticides
, Pages 213-228
15 - Alcohol and Tobacco: leisure Toxins
, Pages 229-244
16 - Electromagnetic Radiation and poisonous Exposure
, Pages 245-258
17 - breathing System
, Pages 261-293
18 - apprehensive System
, Pages 295-326
19 - Developmental Neurotoxicology
, Pages 327-333
20 - Autism: impact of Maternal publicity to Neurotoxic Chemicals
, Pages 335-349
21 - recognition Deficit Hyperactivity affliction (ADHD)
, Pages 351-359
22 - Endocrine System
, Pages 361-380
23 - poisonous Infertility
, Pages 381-400
24 - Teratogens
, Pages 401-415
25 - Immune System
, Pages 417-427
26 - Chemical Sensitivity: a number of Chemical Sensitivity (MCS), persistent Fatigue Syndrome (CFS), Fibromyalgia (FM), and Gulf warfare Syndrome (GWS)
, Pages 429-457
27 - Skin
, Pages 459-472
28 - Musculoskeletal System
, Pages 473-480
29 - Cardiovascular System
, Pages 481-493
30 - Liver
, Pages 495-506
31 - Kidneys
, Pages 507-513
32 - Cancer
, Pages 515-551
33 - adolescence Cancer
, Pages 553-557
34 - melanoma Clusters
, Pages 559-570
35 - Regulatory Requirements
, Pages 573-581
36 - Conclusions and Recommendations
, Pages 583-588
Abbreviations
, Pages 589-592
Index
, Pages 593-600
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Extra info for Human Toxicology of Chemical Mixtures. Toxic consequences Beyond the impact of One-Component Product and Environmental Exposures
Sample text
7. Schwarz M, Appel KE. Carcinogenic risks of dioxin: Mechanistic considerations. Regul Toxicol Pharmacol 2005; 43(1):19–34. 8. Wyde ME, Kirwan SE, Zhang F, et al. Di-n-butyl phthalate activates constitutive androstane receptor and pregnane X receptor and enhances the expression of steroid-metabolizing enzymes in the liver of rat fetuses. Toxicol Sci 2005; 86(2):281–90. 9. Oliver JD, Roberts RA. Receptor-mediated hepatocarcinogenesis: Role of hepatocyte proliferation and apoptosis. Pharmacol Toxicol 2002; 91(1):1–7.
Chemical Toxicology Institute, Foster City, CA, 2000, p. 417. 1 Scope of Exposure and Introduction Since Friedrich Wohler first synthesized urea in 1828, it is estimated that more than 1 million chemicals that were previously unknown in our environment have been synthesized. There are more than 80,000 chemicals manufactured and imported into the United States each year. People are exposed to most of these by air pollution, water pollution, foods and food chain transfers, soil contamination, household use of chemical products, the use of personal care and pharmaceutical products, and industrial contact.
6. Kovacic P, Pozos RS, Somanathan R, Shangari N, O’Brien PJ. Mechanism of mitochondrial uncouplers, inhibitors and toxins: Focus on electron transfer, free radicals and structure-activity relationships. Curr Med Chem 2005; 12:2601–23. 7. Schwarz M, Appel KE. Carcinogenic risks of dioxin: Mechanistic considerations. Regul Toxicol Pharmacol 2005; 43(1):19–34. 8. Wyde ME, Kirwan SE, Zhang F, et al. Di-n-butyl phthalate activates constitutive androstane receptor and pregnane X receptor and enhances the expression of steroid-metabolizing enzymes in the liver of rat fetuses.
Human Toxicology of Chemical Mixtures. Toxic consequences Beyond the impact of One-Component Product and Environmental Exposures by Harold I. Zeliger (Auth.)
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