Read e-book online Autoimmune Reactions PDF

By Sudhir Paul (auth.), Sudhir Paul (eds.)

ISBN-10: 0896035506

ISBN-13: 9780896035508

ISBN-10: 1461216109

ISBN-13: 9781461216100

ISBN-10: 1461272157

ISBN-13: 9781461272151

Autoimmune Reactions tackles basic questions on how the immune approach can break invading microbial pathogens with no inflicting harm to itself and different "self" platforms. The authoritative specialists writing the following discover the mechanistic facets of such autoimmune illnesses as lupus, rheumatoid arthritis, diabetes, and autoimmune thyroid affliction, and the place attainable delineate how malfunctioning immunological mechanisms can result in medical signs. additionally they speak about attainable common mechanisms of autoimmune disease-e.g., molecular mimicry and dysfunctional antigen presentation-and their present boundaries as unifying motives of the ailments defined. additionally, proof for novel immunological phenomena, together with antibody catalysis and the penetration of cells via antibodies, is reviewed, and their attainable organic results are pointed out. The e-book additionally severely surveys the strategies and study that are meant to finally let improvement of palliatives and therapies for autoimmune illnesses, in addition to ways to the long-standing challenge of self-nonself discrimination by way of the immune system.

the great, insightful review supplied in Autoimmune Reactions constitutes the hot typical reference for all practising autoimmunologists, molecular immunologists, mobile and molecular pathologists, and medical immunologists who have to stay on the state of the art of analysis on autoimmune sickness this day.

Show description

Read Online or Download Autoimmune Reactions PDF

Best nonfiction_10 books

Download e-book for iPad: Primate Origins of Human Cognition and Behavior by Tetsuro Matsuzawa (auth.), Tetsuro Matsuzawa (eds.)

Biologists and anthropologists in Japan have performed a vital position within the improvement of primatology as a systematic self-discipline. book of Primate Origins of Human Cognition and behaviour lower than the editorship of Tetsuro Matsuzawa reaffirms the pervasive and artistic function performed via the highbrow descendants of Kinji Imanishi and Junichiro Itani within the fields of behavioral ecology, psychology, and cognitive technology.

New PDF release: The Muscarinic Receptors

Examine on muscarinic receptors is advancing at a unprecedented price. Ten years in the past, the lifestyles of muscarinic receptor sub­ forms was once a logical assumption with merely scattered experimen­ tal aid. the invention that pirenzepine well-known obvious heterogeneity in muscarinic binding websites infused new existence into the matter of subclassifying muscarinic receptors.

Read e-book online Hybridomas and Cellular Immortality PDF

The facility to "immortalize" immunologically-useful cells via hybridization with a special melanoma phone has revolutionized serological experiences and has printed new strength purposes in all fields of organic sciences. This quantity provides the reviews from a hugely winning nationwide symposium on Hybridomas and mobile Immortality held November 1981 in Houston, Texas.

Download PDF by Dr. Keith Hruska, Brenda Kurnik, Masaharu Tsutsumi (auth.),: Phosphate and Mineral Metabolism

We're happy to offer to our readers the court cases of the 6th overseas Workshop on Phosphate and different Minerals which was once held in Verona, Italy, in the course of June 24-26, 1983. It used to be hosted by means of Professor Giuseppe Maschio, Professor of drugs and leader, division of Nephrology on the collage of Verona.

Additional info for Autoimmune Reactions

Example text

Sthoeger, Z. , Tse, D. , Vinciguerra, V. , Allen, S. , Budman, D. , et al. (1989) Production of autoantibodies by CD5-expressing B lymphocytes from patients with chronic lymphocytic leukemia. J. Exp. Med. 169, 255-268. 55. , Binet, J. , and Dighiero, G. (1990) Evidence that chronic lymphocytic leukemia B lymphocytes are frequently committed to productions of natural autoantibodies. Blood 76, 562-569. 56. Kipps, T. , Chen, P. , and Carson, D. A. (1988) Autoantibody associated K light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation, implications for etiology and immunotherapy.

Martin, S. E. and Martin, W. 1. (1975) Interspecies brain antigen detected by naturally occurring mouse anti-brain auto-antibody. Proc. Natl. Acad. Sci. USA 72, 1036-1041. 11. Martin, W. 1. and Martin, S. E. (1975) Thymus reactive IgM auto-antibodies in normal mouse sera. Nature 254, 716-718. 12. Sela, B. , Wang, J. , and Edelman, G. M. (1975) Antibodies reactive with cell surface carbohydrates. Proc. Natl. Acad. Sci. USA 72, 1127-1132. 13. MacKay, I. R. (1983) Natural autoantibodies to the fore - forbidden clones to the rear?

Mazie, J. , Butler-Browne, G. , Whalen, R. , et al. (1983) Murine hybridomas secreting natural monoclonal antibodies reacting with self antigens. J. Immunol. 131, 2267-2272. 21. , and Avrameas, S. (1985) High frequency of natural autoantibodies in normal newborn mice. J. Immunol. 134,765-771. 22. Dighiero, G. (1995) Natural autoantibodies in humans: their relevance in auto-immunity and lymphoproliferative disorders. Forum. Trends Exp. CZin. Med. 5,58-71. 23. Casali, P. and Notkins, A. L. (1988) Probing the human B-cell repertoire with EBV.

Download PDF sample

Autoimmune Reactions by Sudhir Paul (auth.), Sudhir Paul (eds.)

by Donald

Rated 4.63 of 5 – based on 24 votes