The Toxicology of Aflatoxins. Human Health, Veterinary, and by David L. Eaton, John D. Groopman PDF

By David L. Eaton, John D. Groopman

ISBN-10: 0122282558

ISBN-13: 9780122282553

Aflatoxins, typical fungal pollution present in meals and animal feeds, have nice public wellbeing and fitness value. This e-book offers the fundamental and utilized toxicology of aflatoxins, together with analytical identity, agricultural and veterinary implications, toxicology and carcinogenesis in people, and monetary and regulatory difficulties linked to aflatoxin infection and regulate.

Key Features
* Molecular mechanisms of aflatoxin toxicity
* Analytical concerns in sampling and analysis
* Regulatory and monetary concerns linked to aflatoxin illness of nutrients and feed
* Presentation of human and animal toxicology, veterinary, and agricultural concerns regarding aflatoxin illness

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Extra resources for The Toxicology of Aflatoxins. Human Health, Veterinary, and Agricultural Significance

Sample text

And Lewis, G. (1967). Metabolism of aflatoxin in sheep: Excretion pattern in the lactating ewe. Fd. Cosmet. Toxicol. 5, 11-17. Neal, G. E. (1973). Inhibition of rat liver RNA synthesis by aflatoxin B,. Nature (London) 244, 432435. Neal, G. , and Green, J. A. (1983). Requirement for glutathione S-transferase in the conjugation of activated aflatoxin B, during aflatoxin hepatocarcinogenesis in the rat. Chem. Biol. Interact. 45, 259-275. Neal, G. , and Judah, D. J. (1978). Effect of hypophysectomy and AFB, on rat liver.

Epidemiology of aflatoxin carcinogenesis. In "Environmental Cancer" (H. F. Kraybill and M. A. ), pp. 291-318. John Wiley and Sons, New York. Shank, R. C. (1981). Environmental toxicoses in humans. In "Mycotoxins and /V-NitrosoCompounds: Environmental Risks" (R. C. ), vol. 1, pp. 107-140. CRC Press, Boca Raton, Florida. Shank, R. C , Bourgeois, C. , and Candavimal, P. (1971). Aflatoxins in autopsy specimens from Thai children with an acute disease of unknown etiology. Food Cosmet. Toxicol. 9, 501-507.

1992). Temperature acclimation differentially modulates metabolic pathways for AFB, in rainbow trout. Toxicologist 12, 326. Zuckerman, A. , Tsiquaye, K. , and Fulton, F. (1967). Tissue culture of human embryo liver cells and the cytotoxicity of aflatoxins B,. Br. J. Exp. Pathol. 48, 20-27. 2 Biochemical Mechanisms and Biological Implications of the Toxicity of Aflatoxins as Related to Aflatoxin Carcinogenesis ♦ Bill D. Roebuck and Yulia Y. Maxuitenko Aflatoxins are very toxic, particularly to the liver.

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The Toxicology of Aflatoxins. Human Health, Veterinary, and Agricultural Significance by David L. Eaton, John D. Groopman

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