By Dick F. Swaab (Eds.)
This quantity presents a finished realizing of the human hypothalamus, an incredibly complicated constitution that contains a number of very diverse practical devices. It ways the topic in a fashion that has no longer traditionally existed in normal neuropathological investigations of the human mind.
As the hypothalamus was once routinely thought of to be a neuroendocrine constitution, and as a result of little curiosity to neurologists, this quantity explores new findings within the box and the worth they create to the sphere of neurology.
New understandings of the function the hypothalamus performs in reminiscence and a spotlight deficits within the dementias, besides higher facts that the hypothalamus is expounded to indicators and indicators in either neurological and mental problems offer clients within the fields of neuroscience, endocrinology, pediatrics, and psychology with a accomplished source on which to base new learn and exploration.
* a brand new realizing of the function of the human hypothalamus in neurological issues
* medical facts concerning a plethora of neurological issues and the way they relate to the human hypothalamus
* a better realizing of the direct connection among either neurological and mental issues and the function of the hypothalamus in those problems
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Extra info for The Human Hypothalamus: Basic and Clinical Aspects: Part II: Neuropathology of the Human Hypothalamus and Adjacen Brain Structures
A) A Noonan’s syndrome case stained with antibody 747; no. A253/94. (b) The same case as (a), shown at lower magnification. (c) A 6-year-old control; no. 87-305. (d) The same case as (c), shown at lower magnification. Note that there is no clear difference between the Noonan’s syndrome and control cases. Bar = 50 m. (Preparation by A. F. , 1999b). , 1995). , 1978) and children with growth hormone deficiency referred for growth hormone therapy are generally of normal intelligence. However, they do have more learning problems and are also at risk for behavioral problems.
Children with optic nerve hypoplasia in this syndrome are blind in 20–50% of the cases, or severely visually impaired in another 40%. A specific ocular fundus appearance with marked small optic disc and isolated tortuosity of the retinal veins is present. , 2000). , 2000). Septooptic dysplasia has also been described as part of schizencephaly, a structural disorder of cerebral cortical development. , 2000). , 1987). Viral infections, gestational diabetes, and ingestion of large amounts of quinidine in early pregnancy have all been suggested as etiological factors for the sporadic form (Acers, 1981; Costin and Murphree, 1985).
From Aydin and Ghatak, 1994, Fig. ) On MRI, dystopia of the neurohypophysis may closely simulate tumors such as granular cell myoblastomas, astrocytomas, neuronal hamartomas or meningiomas in the hypothalamic area. The absence of symptoms related to the adeno- and neurohypophysis argues in favor of true dystopia of the neurohypophysis and the consideration of this condition in the differential diagnosis of hypothalamic lesions may prevent unnecessary biopsies or neurosurgical procedures (Aydan and Ghatak, 1994).
The Human Hypothalamus: Basic and Clinical Aspects: Part II: Neuropathology of the Human Hypothalamus and Adjacen Brain Structures by Dick F. Swaab (Eds.)