By Aristides Veves, Rayaz A. Malik
During this up-to-date version, major clinical experts seriously evaluate for the overall practitioner the most recent strategies for the scientific administration of diabetic neuropathy. The participants specialise in the sensible facets of diabetic neuropathy and describe intimately the remedies which are at present to be had or anticipated to develop into on hand within the close to destiny. additionally they contain concise discussions of the pathogenesis of diabetic neuropathy.
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Additional info for Diabetic Neuropathy: Clinical Management (Clinical Diabetes)
The Steno-2 Study (39) randomized 160 subjects with type 2 diabetes with microalbuminuria to conventional treatment or to intensive, multifactorial treatment which provided a stepwise implementation of behavior modification and pharmacological therapy that targeted hyperglycemia, hypertension dyslipidemia, and microalbuminuria, along with secondary prevention of cardiovascular disease with aspirin. 8 years. Autonomic neuropathy was defined as heart rate variation on deep breathing. R–R variation higher than 6 beats per minute was considered 20 Wheeler et al.
56. Young MJ, Breddy JL, Veves A, Boulton AJ. The prediction of diabetic neuropathic foot ulceration using vibration perception thresholds. A prospective study. Diabetes Care 1994;17(6):557–560. 57. Pham H, Armstrong DG, Harvey C, Harkless LB, Giurini JM, Veves A. Screening techniques to identify people at high risk for diabetic foot ulceration: a prospective multicenter trial. Diabetes Care 2000;23(5):606–611. 58. Boyko EJ, Ahroni JH, Stensel V, Forsberg RC, Davignon DR, Smith DG. A prospective study of risk factors for diabetic foot ulcer.
Risk factors identified at baseline for incident symmetric polyneuropathy in a Cox proportional hazards model included (Hazard Ratio, 95% CI): type 1 diabetes duration, per 1 SD 16 Wheeler et al. 24). Several other prospective studies were designed to specifically define the incidence of and risk factors for diabetic neuropathy. Of 288 veterans with diabetes but no neuropathy, 20% developed neuropathy after 2 years of follow-up (22). 07 monofilament at one or more of nine sites on either foot. 8).
Diabetic Neuropathy: Clinical Management (Clinical Diabetes) by Aristides Veves, Rayaz A. Malik