Cardiovascular Toxicology, Fourth Edition (Target Organ by Daniel Acosta PDF

By Daniel Acosta

ISBN-10: 1420044737

ISBN-13: 9781420044737

Focusing completely on toxicity to the cardiovascular process, this fourth version of a bestseller emphasizes mechanistic features of toxicity, reading the mobile and molecular results of chemical substances in additional element. Revised and extended, this version includes a new bankruptcy at the hostile results of environmental chemical substances at the cardiovascular process. moreover, the e-book comprises an summary at the opposed results of smoking and secondary smoke. This finished textual content additionally offers new details at the cardiovascular toxicity of antimicrobials, which come with anti-virals and different brokers, in addition to antibacterial brokers and endotoxins.

Show description

Read or Download Cardiovascular Toxicology, Fourth Edition (Target Organ Toxicology Series) PDF

Best toxicology books

Preclinical Development Handbook: Toxicology - download pdf or read online

A transparent, straight forward source to steer you thru preclinical drug developmentFollowing this book's step by step information, you could effectively start up and entire serious stages of preclinical drug improvement. The booklet serves as a basic,comprehensive connection with prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and laws.

Download e-book for iPad: The Role of Glia in Neurotoxicity, Second Edition by Michael Aschner, Lucio G. Costa

Offering the newest examine in glial cellphone functionality gleaned from new thoughts in imaging and molecular biology, The function of Glia in Neurotoxicity, moment version covers a number of facets of glial cells, together with morphology, body structure, pharmacology, biochemistry, pathology, and their involvement within the pathophysiology of neurological ailments.

Veterinary Drug Residues. Food Safety - download pdf or read online

Content material: sturdy animal husbandry perform and residues within the usa / Lester M. Crawford -- Human healthiness hazards linked to drug residues in animal-derived meals / S. F. Sundlof and J. Cooper -- purchaser perceptions and issues approximately veterinary drug residues / Christine M. Bruhn -- eu Union regulatory residue research of veterinary medications : a strategic method / R.

Additional info for Cardiovascular Toxicology, Fourth Edition (Target Organ Toxicology Series)

Sample text

Circulation 2002; 105: 1534–1536. 39. Kang YJ, Li Y, Zhou Z, et al. 5) in rats with acute myocardial infarction. Cardiovasc Toxicol 2002; 2:253–261. 40. Wellenius GA, Saldiva PH, Batalha JR, et al. Electrocardiographic changes during exposure to residual oil fly ash (ROFA) particles in a rat model of myocardial infarction. Toxicol Sci 2002; 66:327–335. 41. Zanobetti A, Schwartz J. Cardiovascular damage by airborne particles: are diabetics more susceptible? Epidemiology 2002; 13:588–592. 42. Herskowitz A, Willoughby SB, Baughman KL, et al.

5). A number of factors may contribute to the more advanced stages of membrane injury. Cellular and organellar membranes consist of a phospholipid bilayer containing cholesterol and glycoproteins. The phospholipid bilayer is maintained by a balance between phospholipid degradation and synthesis. In myocardial ischemia, progressive phospholipid degradation occurs, probably as a result of the activation of one or more phospholipases secondary to an increase of cytosolic calcium or possibly other metabolic derangements (4–6).

Apoptosis in heart failure. Prog Cardiovasc Dis 1998; 40:549–562. 15. Bishopric NH, Andreka P, Slepak T, et al. Molecular mechanisms of apoptosis in the cardiac myocyte. Curr Opin Pharmacol 2001; 1:141–150. 16. Bergmann MW, Loser P, Dietz R, et al. Effect of NF-kappa B Inhibition on TNFalpha-induced apoptosis and downstream pathways in cardiomyocytes. J Mol Cell Cardiol 2001; 33:1223–1232. 17. Green PS, Leeuwenburgh C. Mitochondrial dysfunction is an early indicator of doxorubicin-induced apoptosis.

Download PDF sample

Cardiovascular Toxicology, Fourth Edition (Target Organ Toxicology Series) by Daniel Acosta

by Joseph

Rated 4.74 of 5 – based on 18 votes