By Hongzhe Sun
Arsenic, antimony and bismuth, 3 comparable components of team 15, are all present in hint amounts in nature and feature attention-grabbing organic homes and makes use of. whereas arsenic is prime as a poison - and certainly the illness of groundwater through arsenic is turning into an important ailment in Asia - it additionally has makes use of for the remedy of blood melanoma and has lengthy been utilized in conventional chinese language drugs. Antimony and bismuth compounds are utilized in the sanatorium for the therapy of parasitic and bacterial infections.Biological Chemistry of Arsenic, Antimony and Bismuth is an important evaluation of the organic chemistry of those 3 components, with contributions from a global panel of specialists. issues lined include:chemistry of As, Sb and Bibiological chemistry of arsenicbiological chemistry of Sb and Biarsenic and antimony speciation in environmental and organic samplesarsenic in conventional chinese language medicinearsenic in aquifersbiomethylation of As, Sb and Biuptake of metalloids through cellsbismuth complexes of porphyrins and their power in clinical applicationsHelicobacter pylori and bismuthmetabolism of arsenic trioxide in blood of the extreme promyelocytic leukemia patientsanticancer homes of As, Sb and Biradio-Bi in melanoma therapygenotoxicity of As, Sb and Bimetallomics as a brand new method for As, Sb and Bimetalloproteomics for As, Sb and BiBiological Chemistry of Arsenic, Antimony and Bismuth conveys the fundamental elements of the bioinorganic chemistry of those 3 components, making this e-book a helpful supplement to extra normal bioinorganic chemistry texts and extra really good topical reports. it's going to discover a position at the bookshelves of practitioners, researchers and scholars operating in bioinorganic chemistry and medicinal chemistry.
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Additional resources for Biological Chemistry of Arsenic, Antimony and Bismuth
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Health Canada (2006) Guidelines for Canadian Drinking Water Quality: Technical Document Arsenic, Water Quality and Health Bureau, Healthy Environments, and Consumer Safety Branch, Health Canada, Ottawa. 10. J. J. (1975) Philosophical Magazine, 31, 57–64. 11. N. and Earnshaw, A. (1997) Chemistry of the Elements, Butterworth-Heineman, Oxford. 16 The Chemistry of Arsenic, Antimony and Bismuth 12. B. (1994) in: The Encyclopedia of Inorganic Chemistry (ed. B. King), John Wiley & Sons, Canada Ltd Toronto, pp.
In the inorganic arsenic risk assessments presently done in the USA, it is the biological endpoint of cancer and the linearity associated with its causality that drives the arsenic risk assessment to low exposure levels. Information at many different levels of biological organization can contribute to make a more complete picture of the overall biological processes and also of the individual components that are causally related to one another. Among the many aspects that are important are the temporal sequence of biological changes and the dose-response relationship.
Biological Chemistry of Arsenic, Antimony and Bismuth by Hongzhe Sun