Get An introduction to immunotoxicology PDF

By Jacques Descotes

ISBN-10: 0203362543

ISBN-13: 9780203362549

ISBN-10: 0203379349

ISBN-13: 9780203379349

ISBN-10: 074840306X

ISBN-13: 9780748403066

Lyon-RTH Laennec college of medication, France. creation to key immunotoxicological matters. Considers the well-being results of immunotoxicity and addresses the state of the art tools used to notice and evaluation unforeseen immunotoxic results of xenobiotics, either preclinically and clinically. For undergraduate and graduate scholars. Hardcover, softcover additionally on hand.

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Oxford: Oxford Press. P. (1995) Bacterial complications of transplantation: diagnosis and treatment. J. Antimicrob. , 36, Suppl. B, 59–72. , BERD, D. J. (1989) Effects of anticancer drugs on the immune system in humans. Semin. , 16, 230–253. E. P. (1993) Respiratory infections in immunocompromised patients. Immunol Allergy Clin. N. , 13, 193–204. D. (1995) Viral complications after transplantation. J. Antimicrob. , 36, Suppl. B, 91–106. HARWOOD, J. (1989) Lessons from the seal epidemic. New Scientist, 18 February, 38–42.

VIAL, T. and DESCOTES, J. (1994) Clinical toxicity of the interferons. Drug Safety, 10, 115–150. VIAL, T. and DESCOTES, J. (1995a) Immune-mediated side-effects of cytokines in humans. Toxicology, 105, 31–57. VIAL, T. and DESCOTES, J. (1995b) Clinical toxicity of cytokines used as hemopoietic growth factors. Drug Safety, 13, 371–406. VIAL, T. and DESCOTES, J. (1996) Drugs acting on the immune system. ), pp. 1090–1165. Amsterdam: Elsevier Sciences. WILLIAMS, T. C. (1986) Inhibition of antipyrine metabolism by interferon.

One major issue is the concept of functional reserve capacity of the immune system: it is well recognised that redundant effector and/ or regulatory mechanisms are generally combined to mount a normal immune response. Therefore, when one such mechanism is impaired in relation to immunotoxic exposure, one or several mechanism(s) can exert their compensatory influence, so that the resulting consequence is the lack of overt change. Although antimicrobial resistance was consistently shown to be markedly impaired in patients treated with potent immunosuppressive agents, it is more difficult to identify whether and to what extent antimicrobial resistance is impaired following exposure to chemicals which depress, but do not totally abrogate, the immune response, that is to say immunodepressive chemicals.

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An introduction to immunotoxicology by Jacques Descotes

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