By Shayne Cox Gad; Christopher P Chengelis
ISBN-10: 0122722507
ISBN-13: 9780122722509
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Extra info for Acute toxicology testing
Example text
H o w large an effect will be considered biologically significant? This is a 2 Acute Toxicology Program: Study Design and Development 29 question which can only be resolved by reference to experience or historical control data. III. , what answers are possible to both our subquestions and our major question? - - H o w do we use these answers? - - D o the possible answers offer a reasonable expectation of achieving the objectives that caused us to initiate the study? - - W h a t new questions may these answers cause us to ask?
And Lippold, B. H. (1982). Dermal and Transdermal Absorption. Wissenschaftliche Verlagsgesellschaft, Stuttgart. Bronough, R. , and Maibach, H. I. (1985). Percutaneous Absorption. Dekker, New York. Choman, B. R. (1963). Determination of the response of skin to chemical agents by an in vitro procedure. J. Invest. Dermatol. 44, 177-182. Code of Federal Regulations (CFR) (1984). Transportation, Title 49: Part 173, Appendix A - Method of Testing Corrosion to Skin, Revised; November 1. Consumer Product Safety Commission (CPSC) (1980).
1982). Dermal and Transdermal Absorption. Wissenschaftliche Verlagsgesellschaft, Stuttgart. Bronough, R. , and Maibach, H. I. (1985). Percutaneous Absorption. Dekker, New York. Choman, B. R. (1963). Determination of the response of skin to chemical agents by an in vitro procedure. J. Invest. Dermatol. 44, 177-182. Code of Federal Regulations (CFR) (1984). Transportation, Title 49: Part 173, Appendix A - Method of Testing Corrosion to Skin, Revised; November 1. Consumer Product Safety Commission (CPSC) (1980).
Acute toxicology testing by Shayne Cox Gad; Christopher P Chengelis
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