By Brian Charlesworth, Deborah Charlesworth (auth.), Ronny C. Woodruff, James N. Thompson Jr. (eds.)
Although debated because the time of Darwin, the evolutionary function of mutation continues to be arguable. In over forty chapters from prime specialists in mutation and evolutionary biology, this e-book takes a brand new examine either the theoretical and experimental size and importance of recent mutation. Deleterious, approximately impartial, invaluable, and polygenic mutations are thought of of their results on health, existence heritage qualities, and the composition of the gene pool. Mutation is a phenomenon that attracts cognizance from many various disciplines. hence, the wide reports of the literature can be priceless either to confirmed researchers and to these simply starting to research this box. via up to date studies, the authors supply an insightful review of every subject after which percentage their most up-to-date principles and discover debatable elements of mutation and the evolutionary strategy. From themes like gonadal mosaicism and mutation clusters to adaptive mutagenesis, mutation in mobilephone organelles, and the extent and distribution of DNA molecular alterations, the basis is determined for carrying on with the talk in regards to the position of mutation, health, and flexibility. it's a debate that would have profound effects for our knowing of evolution.
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Extra info for Mutation and Evolution
1993. Mutation accumulation in finite outbreeding and inbreeding populations. Genet. Res. 61: 39-56. , 1995. A method for estimating the numbers of synonymous and nonsynonymous substitutions per site. J. Mol. Evol. 41: 1152-1159. P. & M. Kimura, 1970. An Introduction to Population Genetics Theory. Harper and Row, New York. , Y. Van de Peer & R. De Wachter, 1997. Database on the structure of large ribosomal subunit RNA. Nucl. Acids Res. 25: 117-122. De Rijk, P. & R. De Wachter, 1993. DCSE, an interactive tool for sequence alignment and secondary structure research.
USA 94: 3823-3827. T. & M. Lynch, 1996. Estimate of the genomic mutation rate deleterious to overall fitness in Escherichia coli. Nature 381: 694-696. , K. Tamura & M. Nei, 1993. 01. Penn. , University Park, PA. Kumazawa, Y. & M. Nishida, 1993. Sequence evolution of mitochondrial tRNA genes and deep-branch animal phylogenetics. J. Mol. Evol. 37: 380-398. , 1994. Risk of population extinction from new deleterious mutations. Evolution 48: 1460-1469. Li, W-H. & D. Graur, 1991. Fundamentals of Molecular Evolution.
E. M. Sharp, 1989. Fast and sensitive multiple sequence alignments on a microcomputer. CABIOS 5: 151-153. , 1994. Error thresholds and stationary mutant distributions in multi-locus diploid genetics models. Genet. Res. 63: 63-78. Hill, WG. & A. Robertson, 1966. The effect of linkage on limits to artificial selection. Genet. Res. 8: 269-294. , J. A. Williams & A. Sidow, 1994. Gene duplications and the origins of vertebrate development. Devel. Suppl. 125-33. , 1994. The distribution of mutation effects on viability in D.
Mutation and Evolution by Brian Charlesworth, Deborah Charlesworth (auth.), Ronny C. Woodruff, James N. Thompson Jr. (eds.)