Alex Stagnaro-Green (auth.), Rhoda H. Cobin M.D., David King's Malignant Tumors of the Thyroid: Clinical Concepts and PDF

By Alex Stagnaro-Green (auth.), Rhoda H. Cobin M.D., David King Sirota M.D. (eds.)

ISBN-10: 146139127X

ISBN-13: 9781461391272

ISBN-10: 1461391296

ISBN-13: 9781461391296

Thyroid carcinoma is an unusual malignan­ ing the to be had non-human traces, as types cy. within the overwhelming majority of sufferers, if taken care of for mobile cycle reports and oncogene/anti­ adequately, it's linked to a benign oncogene rules, simply because they're unaware medical direction. Why then does it carry a con­ of the usually basic dichotomy among tinuing fascination for thus many physicians? thyroid malignancy and diagnosis. 3rd, the the answer's most likely at once established very nature of the benign scientific path has steered to the main health and wellbeing study fund­ at the very benign nature of so much thyroid ing firms that thyroid melanoma isn't necessary maligllancies. whereas there are poor excep­ of research in a time of scarce assets. tions, the follicular and papillary thyroid can­ not anything will be farther from the reality. cers behave in a fashion particularly alien to "common" This pleasing scientific path is the very cause neoplasia, due to the fact they develop and metastasize why the research of human thyroid melanoma has the slowly. We think that if in basic terms lets below­ strength for contributing additional to our enjoyable­ stand this sort of remodeled kingdom, we'd be able to research very much in regards to the common and damental realizing of malignancy and, irregular legislation of the mobile cycle and im­ possibly extra importantly, the mechanisms via end up our knowing of melanoma. which the human physique can face up to neoplastic although, contemporary advances within the biology of cells.

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Follicular carcinoma of the human thyroid gland. An ultrastructural study with emphasis on scanning electron microscopy. Diagn HistopathoI1982;5:113-127. 52. Lukacs GL, Balazs G, Zs-Nagy I. Cytoflourimetric measurements on the DNA contents of tumor cells in human thyroid gland. J Cancer Res Clin Oncol 1979;95:265-271. 53. Grant CS, Hay ID, RyanJJ, Bergstrah EJ, Reunwater LM, Guillnar JR. Diagnostic and prognostic utility of flow cytometric DNA measurements in follicular thyroid tumors. World Jnl of Surgery, 1990;14:283-289.

Thompson NW, Nishiyama RH, Harness JK. Thyroid carinoma: Current controversies. In: Ravitch MM, Steicher FM, eds. Current problems in Surgery 15, No. 11. Chicago: Yearbook Medical Publishers, 1978:1-15. 22. Cady B, Sedgwick CD, Meissner WA, Bookwalter JR, Romagosa V, Werber J. Changing clinical, pathologic, therapeutic, and survival patterns in differentiated thyroid carcinoma. Ann Surg 1976; 184:541-553. 23. Boehm T, Rothouse L, Wartofsky L. Metastatic occult follicular thyroid carcinoma. JAMA 1976;235:24202421.

Infants and children are at greater risk than adults. This may be due to growth factors other than thyroid-stimulating hormone (TSH), that are operative in infants and children, but absent in adults. The growth of the thyroid from 20 mg grams at birth to 25 g in adulthood may not be mediated exclusively by thyroid stimulating hormone. The existence of other growth factors has been postulated, but not proven. 32,33,34 For unknown reasons, the incidence of carcinoma of the thyroid gland is greater in females than in males, in both irradiated and nonirradiated populations.

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Malignant Tumors of the Thyroid: Clinical Concepts and Controversies by Alex Stagnaro-Green (auth.), Rhoda H. Cobin M.D., David King Sirota M.D. (eds.)

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