By Ana Maria Gonzalez-Angulo, Flavia Morales-Vasquez (auth.), Dihua Yu, Mien-Chie Hung (eds.)
ISBN-10: 0387740376
ISBN-13: 9780387740379
In Breast melanoma Chemosensitivity, a gaggle of global prime specialists evaluation severe points of resistance to systemic treatment in breast melanoma sufferers. starting with a medical evaluation of the matter Breast melanoma Chemosensitivity strikes directly to specialise in the most recent findings of molecular mechanisms of drug resistance. those comprise in-depth discussions on multidrug resistance through P-glycoprotein and the multidrug resistance protein kinfolk, resistance to healing agent-induced apoptosis, phone cycle deregulation, deregulation of DNA fix, lack of tumor suppressor genes, integrin-mediated adhesion, insulin-like development elements, epidermal progress issue, and ErbB2 in modulating breast melanoma reaction to systemic treatment, in particular, definite chemotherapeutic brokers. Breast melanoma Chemosensitivity offers an instance of utilizing novel methods for chemosensitization of breast melanoma cells that provides readers an idea concerning the destiny path in breast melanoma treatment.
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Bates SE, Robey R, Miyake K et al. The roles of half-transporters in multidrug resistance. J Bioenergetics and Biomem 2001; 33:503-517. 36. Jonker JW, Buitelaar M, Wagenaar E et al The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria. Proc Natl Acad Sci USA 2002; 99:15649-15654. 37. Leonessa F, Clarke R. ATP binding cassette transporters and drug resistance in brease cancer. Endocrine-related Cancer 2003; 10:43-73. 38. Beck WT, Grogan TM, Willman CL et al.
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Annals Oncol 2002; 3:197-207. 40. Thomas E, Holmes FA, Smith TL et al. The use of alternate, noncross-resistant adjuvant chemotherapy on the basis of pathologic response to a neoadjuvant doxorubicin-based regimen in women with operable breast cancer: Long-term results from a prospective randomized trial. J Clin Oncol 2004; 22:2294-2302. 41. Strumberg D, Nitiss JL, Rose A et al. Mutation of a conserved serine residue in a quinolone-resistant type II topoisomerase alters the enzyme-DNA and drug interactions.
Breast Cancer Chemosensitivity by Ana Maria Gonzalez-Angulo, Flavia Morales-Vasquez (auth.), Dihua Yu, Mien-Chie Hung (eds.)
by Michael
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