By Michel Burnier, Robert W. Schrier (auth.), Alberto Amerio, Pasquale Coratelli, Vito M. Campese, Shaul G. Massry (eds.)
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Extra resources for Acute Renal Failure: Clinical and Experimental
However, there are consistent differences in the criteria for the selection of those patients who might benefit from the diagnostic procedure and in how frequently i t really should be applied . The the use of biopsy in renal disease in different atti tudes toward general are probably responsible for this disagreement, and may explain why the percentage of biopsied patients in the total number of patients with intrinsic acute renal failure (ARF) ranged between 12% and 92% in the different series reported in the literature (Table I).
Bulger, R. , Purcell, D. J. 11 and Dobyan, D. : Endothelial characteristic'8 of glomerular capillaries in normal and mercuric chloride-induced acute renal failure in the rat. J. CLIN. INVEST. 72: 128-141, 1983. , D'Agostini, R. , Freedman, M. , Scott, W. W. , Siegelman, S. S. and Heptinstall, R. : Beneficial effect of propranolol in a histologically appropriate model of postischemic acute renal failure. AMER. J. PATHOL. 88: 163, 1977. , Dohoux, P. and Sraer, J. : The pathology of acute renal failure due to interstitial nephritis in man with comments on the role of interstitial inflammation and sex in gentamicin nephrotoxicity.
Obviously, one must wait long enough to carefully control hypertension and to permit a rise in platelet count, before one can proceed to biopsy with sufficient safety. Table 11. ) :::> [f) 38 ::s [f) H [f) 0 z < H GLOMERULAR DISEASE .... , .... GI 00 Q\ >< .... ,0 .... ) ~ ~ 5% 23% 55% 48% GI 00 CIl ::s ::;:: 26% We prefer sometimes,in these circumstances,to use surgical biopsy instead of percutaneous biopsy,even though severe complications may occur even with the former procedure. In conclusion, the criteria we use for deciding to take biopsies from patients with intrinsic ARF are as folIows: 1) ATN is suspected, but there is no obvious cause for it (exposure to toxins, hypotension, sepsis, etc).
Acute Renal Failure: Clinical and Experimental by Michel Burnier, Robert W. Schrier (auth.), Alberto Amerio, Pasquale Coratelli, Vito M. Campese, Shaul G. Massry (eds.)