Read e-book online Peptic Ulcer Disease: Basic and Clinical Aspects: PDF

By G. F. Nelis M.D. (auth.), G. F. Nelis MD, J. Boevé M.D., J. J. Misiewics B.Sc, M.B., F.R.C.P. (eds.)

ISBN-10: 9400950349

ISBN-13: 9789400950344

ISBN-10: 940108730X

ISBN-13: 9789401087308

Despi te a sluggish lessen within the prevalence of peptic ulcer within the Western international up to now decade, common practitioners, physicians, gastroenterologists, and surgeons care for sufferers struggling with peptic ulcer and its issues virtually day-by-day. it's been predicted that a few 10% of the inhabitants within the Western international turns into af­ flicted by way of peptic ulcer once or more and plenty of of them have continual relapsing affliction. This lays a heavy burden at the sum of money that is spent mostly healthiness care. lately our knowing of peptic ulcer sickness has in­ creased significantly, yet massive gaps in our wisdom stay. initially the rise in our wisdom has been encouraged by means of the advance of fibre-optic endoscopy within the sixties, and later through the improvement of latest surgical ideas and medicine within the seventies. New insights into the pathophysiology of the sickness resulted from those advancements and revived the medical curiosity in peptic ulcer sickness. besides the fact that, the sector continues to be advanced and the stories are be­ devilled via the massive variety of variables which could impact the implications. within the symposium 'PEPTIC ULCER this present day' we've attemp­ ted to collect contemporary wisdom on easy and medical features of peptic ulcer disease.

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Extra resources for Peptic Ulcer Disease: Basic and Clinical Aspects: Proceedings of the Symposium Peptic Ulcer Today, 21–23 November 1984, at the Sophia Ziekenhuis, Zwolle, The Netherlands

Sample text

_ ko",. · .. , • -" 9 a l l FRACTI(lH Fieure 1:. The binding of 125I_[Leu 15)_G 17 to cell fractions separated by elutriation. Fractions ot~increasing size were collected using a Beckman elutriator rotor. Parietal, cheif, and mucous cells were identified on cytocentrifuge slides stained with periodic acid Schiff. In the left panel, 125I-[Leu I5 )-G17 binding in fmol/I0 6 cells and the percentage content of parietal cells, mucous cells (PAS +) and mast cells, the latter stained with toluidine blue .

Competitive inhibition of histamine-stimulated HC-aminopyrine accumulation into parietal cells by cimetidine. Canine parietal cells were stimulated by the indicated concentrations of histamine in the presence of the 4 indicated concentrations of cimetidine . uM C (11 o ao ~ -0 :.. 3 \ Figure 3. Competitive inhibition of cholinergic-stimulated HC-aminopyrine accumulation into parietal cells by atropine. Canine parietal cells were stimulated by the indicated concentrations of carbachol in the presence of the 4 indicated concentrations of atropine.

Smith MP. Decline in duodenal ulcer surgery. JAMA 1977;237:987 -88. 32. Watkins RM, Dennison AR, CollinJ. What has happened to perforated peptic ulcer? Br J Surg 1984;71:774-6. 33. Fineberg HV, Pearlman LA. Surgical treatment of peptic ulcer in the United States. Trends before and after the introduction of cimetidine. Lancet 1981; 1: 1305 -7. 34. Kreuning J. Genetic aspects of peptic ulcer. In: Nelis GF, Boeve, Misiewicz JJ (Eds). Peptic ulcer today. Dordrecht: Martinus Nijhoff Publishers, 1985:173 - 81.

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Peptic Ulcer Disease: Basic and Clinical Aspects: Proceedings of the Symposium Peptic Ulcer Today, 21–23 November 1984, at the Sophia Ziekenhuis, Zwolle, The Netherlands by G. F. Nelis M.D. (auth.), G. F. Nelis MD, J. Boevé M.D., J. J. Misiewics B.Sc, M.B., F.R.C.P. (eds.)


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