By Rafael Carrion MD, Derek Bochinski MD (auth.), Gregory A. Broderick MD (eds.)
With the arrival of such oral medicines as Viagra®, Cialis®, and Levitra® for the remedy of erectile disorder (ED), the load of first sufferer evaluate has fallen at the fundamental care supplier. In Oral Pharmacotherapy for Male Sexual disorder: A consultant to medical administration, hugely skilled urologists and health care provider researchers overview every one point of male sexual disorder (interest, functionality, and orgasm) and their implications for remedy. The authors deal with a large choice of medical concerns, starting from universal clinical probability components for ED to the review and administration of fellows who've abnormal displays that require centred trying out; from diabetic ED to the protection overview of PDE inhibitors for cardiac sufferers; and from blend drug treatment for refractory sufferers to neuropharmacological cures. advice is additionally supplied for vacuum erection units and surgical implants, the function of self-medication with supplements, the administration of post-prostatectomy ED, and the rising pharmaceutical treatments for speedy ejaculation. at the pharmaceutical part, the authors summarize the pharmacology and improvement of PDE-type five inhibitors, assessment the preclinical facts and five years of postmarketing facts on Viagra®, research the preclinical facts on Levitra®, and speak about the layout and behavior folks medical trials of Cialis®.
Authoritative and informative, Oral Pharmacotherapy for Male Sexual disorder: A consultant to medical administration clarifies for urologists, kinfolk physicians, and internists all of the diagnostic techniques to male sexual disorder, in addition to the pharmacological recommendations on hand for its secure and potent management.
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Additional resources for Oral Pharmacotherapy for Male Sexual Dysfunction: A Guide to Clinical Management
1994) Benign prostatic hyperplasia: effects on quality of life and impact on treatment decisions. Urology 44:629–636. 38. Calvert RC, Khan MA, Thompson CS, et al. (2001) Alterations in nictic oxide signaling provides insight into the pathophysiology of erectile dysfunction associated with benign prostatic hyperplasia. Presented at the American Urological Association Annual Meeting, Anaheim, CA. 40 Schiff and Mulhall 39. Chang S, Hypolite JA, Wein AJ, et al. (2001) The effect of bladder outlet obstruction on rabbit corpus cavernosum smooth muscle contractility.
Complete ED was found in 5% of men by 40 yr of age and in 25% of men by 75 yr of age. When extrapolated to the male population in general, this analysis estimated that 30 million American men and 100 million men worldwide have ED. In addition to epidemiology, this study also examined risk factors associated with ED. Medical conditions that increased the risk of ED after controlling for age in this study included cardiovascular disease, hypertension, diabetes, depression, anger disorders, and arthritis.
Some of this variation is explained by differences in the definition of depression. Depressed mood and poor quality of life are very common among men with ED, but clinical depression is not as common. Therefore, until a consistent definition of depression is used and a large sample is followed, any relationship between ED and depression must be regarded with skepticism. Medications A plethora of medications have been associated with ED. Studies suggest that as many as one-quarter of patients seen in general medical practices have ED as a result of a medication that they take (58).
Oral Pharmacotherapy for Male Sexual Dysfunction: A Guide to Clinical Management by Rafael Carrion MD, Derek Bochinski MD (auth.), Gregory A. Broderick MD (eds.)