By Dr. Dr. Roland R. Schmoker (auth.)
Since 1958 the organization for the examine of inner Fixation (ASIF) has labored to set up the experimental and biomechanical prin ciples of the operative therapy of fractures. it's been confirmed that quick, pain-free mobilization, made attainable by means of reliable inner fixation, is the major to restoring functionality in a fractured extremity. an analogous rules have been utilized in 1972173 by means of Roland Schmoker, who built a common plate and complex tool set designed at the start for the remedy of comminuted fractures of the mandible. to increase the purposes of his plate to reconstructions after ex tensive tumor resections, he supplemented the gadget with tem poromandibular joint prostheses and anchoring components for the at tachment of dentures. He first verified the useful balance of those implants experimentally in sheep. Later he discovered that the minipig had a extra human-like jaw form and masticatory motion, and so he verified the implants in 37 mini pigs that underwent vast mandibular re sections with out bone grafting, utilizing sequential dye injections and postoperative weight achieve to chart the development of osseous regener ation. Seven different animals weren't operated and served as controls.
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Additional resources for Functional Reconstruction of the Mandible: Experimental Foundations and Clinical Experience
V. v. v. m. v. 2 Experimental Design Division into groups (Tables 2 and 3): The animals were separated into groups on the basis of the variables stated earlier (number of screws and plate length; with or without abutments; mode of placement of abutments; extraoral or combined intra- and extraoral approach; with or without periosteal separation in the area of the alveolar ridge; with or without creation of a skin flap; survival time 3-4 months or over 3 years). Five groups were designated: Group 1 was a control group composed of 7 minipigs (animals 1-7) that were not operated on but were maintained under the same conditions as the experimental animals.
6 Technique of Examination Necropsy specimens were fixed in precooled 50% alcohol. One week later we obtained an axial radiograph of the specimen and also a lateral t"adiograph after dividing the mandible anteriorly (Figs. 57- 59) (see list on p. 40). lm), unstained or spot stained in basic fuchsin, for each mandible from the areas of the plate anchorage, glenoid fossa and abutment (Fig. 60) and from the contralateral temporomandibular joint, following the method of SCHENK . The sequential dye labels were studied by fluorescent microscopy (Figs.
Complications not related to the experiment developed in 2 animals. Animals 24 and 32 from groups 3 and 4 sustained a mandibular fracture caused by a mishap during injection of the dye. This led in animal 24 to a loosening of the plate anchorage and subsequent infection, so that the displaced reconstruction plate finally was attached only to the fractured, devitalized fragment. This animal lost a total of 3 kg. In animal 32 the undisplaced fracture occurred outside the area of the plate anchorage.
Functional Reconstruction of the Mandible: Experimental Foundations and Clinical Experience by Dr. Dr. Roland R. Schmoker (auth.)