Mark D'Esposito's Functional MRI: Applications in Clinical Neurology and PDF

By Mark D'Esposito

ISBN-10: 1435626761

ISBN-13: 9781435626768

ISBN-10: 184214295X

ISBN-13: 9781842142950

Useful imaging has the aptitude to bare alterations within the pathophysiology of tissues and organ structures, mapping the development and severity of disorder, uptake of gear, and the restoration of tissues following trauma, illness episodes or surgical procedure. during this authoritative new paintings, best experts in neurology and neuroimaging current an replace at the MRI and puppy research of ailments of the valuable anxious approach. An insightful reference for a person operating within the box, this paintings discusses how those new applied sciences can be utilized to enquire crucial issues encountered in medical neurology and psychiatry, starting from power revolutionary ailments akin to Alzheimer's, episodic disruptions of functionality as visible in epilepsy, and the delicate alterations attributable to drug dependency and abuse.

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Additional resources for Functional MRI: Applications in Clinical Neurology and Psychiatry

Sample text

For example, one might find that a propensity for seizure activity in the mesial temporal lobes is marked by an oscillation in the fMRI signal of a particular frequency from this location. 26 Distinguishing such pathological signals from background noise and imaging artifacts presents the primary challenge for this type of application of fMRI. Diagnostic and therapeutic classification There is a broad range of clinical applications of fMRI that might fall under the title diagnostic and therapeutic classification.

Zarahn E, Aguirre GK, D’Esposito M. Empirical analyses of BOLD fMRI statistics. I. Spatially unsmoothed data collected under null-hypothesis conditions. NeuroImage 1997; 5: 179–97. Aguirre GK, Detre JA, Alsop DC. Experimental design and the relative sensitivity of BOLD and perfusion fMRI. NeuroImage 2002; 15: 488–500. D’Esposito M, Zarahn E, Aguirre GK, Rypma B. The effect of normal aging on the coupling of neural activity to the bold hemodynamic response. NeuroImage 1999; 10: 6–14. D’Esposito M, Deouell LY, Gazzaley A.

Simultaneous measurements of microflow and evoked potentials in the somatomotor cortex of the cat brain during specific sensory activation. Pflugers Arch 1979; 380: 85–9. Malonek D, Grinvald A. Interactions between electrical activity and cortical microcirculation revealed by imaging spectroscopy: implications for functional brain mapping. Science 1996; 272: 551–554. Thulborn KR, Waterton JC, Matthews PM, Radda GK. Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field.

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Functional MRI: Applications in Clinical Neurology and Psychiatry by Mark D'Esposito


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